Male or female, it doesn't matter. I think Sagara Souske from Full Metal Panic is dead sexy.

I think the other main character from FMP!, Kaname Chidori (Sosuke's "girlfriend"), is frikkin' hot.

But for my choice for the hottest... Either Faye Valentine from Cowboy Bebop or Major Motoko Kusanagi from Ghost in the Shell. The way in which Wendee Lee and Mary McGlynn voice those two characters, respectively, just adds to their hotness.

Urd from Aa! Megami-sama! for one..

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Leemanism.com - tiny, but not fangless

i liked the one from hmm, SHUFFLE!!! most of da chicks there were pretty hawt, coz the anime was made from hentai, so its go lyk...hawt chicks there

hmmmmmmmmmm toy (from ceres by yuu watase) or takuto (from full moon wo sagashite) there both hot

I think Yoruichi Shihouin from Bleach has got to be one of the hottest female anime characters. She's got looks, power, speed, smarts, funny sense of humour (when training Ichigo) AND IS A NINJA!! How cool is that?!

Sailor Mercury hands-down. Soft-spoken, humble, smart as a bee, and some awesome blue hair!

I think Homura from Saiyuki is hot (i also love his voice *drools*). Ban from Get Backers is another one. Athrun Zala from Gundam Seed was hot. Zack from the FF7 anime OVA was quite nice as well.

Toujou Aya, Tsukasa Nishino... and almost every girl except Satsuki from Ichigo 100%
Tifa from FFVII - AC
Chii from Chobits and the two girls from DearS