Heero and Relena from Gundam Wing are my faves

HECK YES i love konata. i have a phonecharm of her and just bought the dub dvd today =3

Gen and Melfina from Outlaw Star.

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Ash and Pikachu. Hands Down.

sora and khairi...

Eureka and Renton From Eureka 7..
I nearly cried at the end of the anime tho they finally get together.. so happy, I can't wait for the Eureka 7 movie to launch! ^^

Def Keitaro and Naru from Love Hina.

Chrno and Rosette from Chrno Crusade
Van and Hitomi from The Vision of Escaflowne
Spike and Julia from Cowboy Bebop
Kiba and Cheza from Wolf's Rain
Robin and Amon from Witch Hunter Robin
Keitaro and Naru from Love Hina
Inuyasha and Kagome from Inuyasha
Kenshin and Tomoe from Samurai X
Tadahiro and Yuzu from Shrine of the Morning Mist
Demon Eyes Kyo and Shiina Yuya from Samurai Deeper Kyo
Howl and Sophie from Howl's Moving Castle
Shirō Emiya and Saber/Archer and Rin Tōsaka from Fate/Stay Night

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I'm pretty much of a yuri fangirl, so be warned...

I like:
Yumi & Sachiko (Marimite)
Aeru & Neviril (Simoun)
Nagisa & Shizuma (Strawberry Panic)
Yoruichi & Soi Fon (Bleach)
Ichigo & Rukia (Bleach)

But there are so many other anime couples that I ship, also non-yuri ones. I just never manage to remember every one.
I also make couples in Video Games often.

hmmm..... i think ill go w/ Issuzu "Rin" Sohma and Hatsuharu Sohma in Fruits Basket.