For a weapon: Any of the Ragnarok swords from the Final Fantasy games, the minigun from the Serious Sam games, Barry Burton's magnum from Resident Evil(GC), and the discarmor from Rygar.

For magic: I'm partial to anything ice-based, I also like Flare from the Final Fantasy games.

Games:

Tales of Symphonia
Tales of the Abyss
Tales of Vesperia

Yes they are a series but they are unrelated in story and therfore not bound to the sucky sequal cliche

Fire Emblem
Fire Emblem: Sacred Stones (it was easy but still very fun)
Fire Emblem: Path of Radiance
Fire Emblem Radiant Dawn

Again, a series, but they are not story related (except for Path of Radiance and Radiant Dawn)

And Call of Duty 4 was pretty good for a shooter.


Weapons:

Soul Crush (Tales of the Abyss)
Master Sword (Legend of Zelda)
Ragnell (Fire Emblem: Path of Radiance & Radiant Dawn)
Beam Sword (Super Smash Bros. Brawl)

hyper beam - super metroid
Tsumikiri J-Sword - phantasy star online ep1, 2 for gc.
infinate rocket in RE4 lol

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samus rocks!

southern cross from star ocean second story

knights of the round (ff7) - just sucks to sit and watch it every effing time

The Cerebral Bore from Turok 2

How the fuck would you use it in combat? It's a two-handed weapon, so you can't use another weapon in tandem with it.

I'd say Ebony and Ivory from DMC are pretty fucking cool, but my heart belongs to the M14.

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Check it out, man. Game over, too.

evokers of persona 3